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Associate Director, Bioanalytical and Biomarker Development

RecursionFull-timeRemoteOct 17, 2024
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Your work will change lives. Including your own. 

The Impact You’ll Make

As part of the Recursion Clinical Development team, you will work within a top-tier multidisciplinary team tasked with efficiently navigating Recursion's clinical candidates to proof of concept and approval as safe and efficacious therapeutics for patients with unmet need. Your understanding of the regulatory, scientific and logistic aspects of the analysis of bioanalytical and biomarker samples will empower pre-clinical and clinical decision making across all target indications.

In this role, you will:

  • Define and execute bioanalytical and biomarker strategies for compounds in support of Recursion's clinical pipeline.
  • Utilize your deep understanding of quantitative and qualitative bioanalysis to support the assessment of different types of analytes ranging from small molecules to proteins and DNA/RNA. 
  • Synthesize and interpret in-house and external data spanning the entire spectrum of drug discovery and development. 
  • Manage vendors that develop, validate and execute bioanalytical and biomarker assays for nonclinical studies and clinical trials.

You can expect to work on multiple projects at the same time in a fast-paced and exciting environment. On normal workdays, you can expect to:

  • Interface with internal Recursion study and clinical teams to define and execute bioanalytical and biomarker strategy
  • Liaise with external vendors to propose, trouble-shoot and validate analytical methods across a wide range of platforms including LC/MS/MS, ligand-binding, flow cytometry, DNA and RNA sequencing and more.Coordinate vendor selection, contracting, and budgeting for pre-clinical and clinical bioanalytical packages.
  • Support pharmacokinetic and pharmacodynamic modelers with high quality, fit-for-purpose data.
  • Partner with Clinical Operations to ensure appropriateness of sample collection, transport and analysis.
  • Work with Quality and Regulatory Assurance to confirm analysis at the appropriate rigor to serve desired reporting requirements.

Location:

Making Salt Lake City your home base is ideal, however, we will consider remote work for this position. We ask that remote employees commit to regular on-site visits for routine work and departmental events. 

The Team You’ll Join 

As Associate Director of Bioanalytical and Biomarker Development you will be reporting to the Director of Bioanalysis and Biomarker Development. You will be an essential member of the Development Sciences team within Clinical Development. The Development Sciences group is tasked with the translational activities required to successfully move a program from discovery to development including translational PK/PD modeling, clinical pharmacology, clinical bioanalysis and biomarker development to support selection of the right patient and the right dose. The goal of the group is to use the Recursion Operating System and mindset to rapidly and effectively transition new or repositioned molecules from advanced discovery candidates through IND filings and provide continued support throughout the clinical development program.

The Experience You’ll Need

  • PhD with 2+ years, MS with 5+ years, or Bachelor's with 10+ years of Industry experience
  • Degree in chemistry, biology, biochemistry, or related discipline with an emphasis on analytical techniques suitable for the extraction and analysis of target compounds from complex biological matrices.
  • Previous experience working with or within CRO organizations.
  • Previous experience working in the biopharma industry preferred
  • Strong working knowledge of regulations, guidelines, standards that guide collection and utilization of non-clinical and clinical samples and data
  • Familiarity with regulatory expectations (FDA and EMA) and industry's best practices in bioanalytical and biomarker/diagnostic assay method development and validation
  • Ability to diagnose and solve complex technical and scientific problems
  • An understanding of principles of relationship management across diverse internal and external stakeholders

How You’ll be Supported

You will be introduced to the Recursion mindset and Recursion operating system through a series of in-person and online tools to help you quickly understand and embrace the unique culture of Recursion.You will be introduced to colleagues throughout the Recursion organization that can help guide you through both the traditional and Recursion-specific elements of your role. You will have the opportunity to attend or join sub-teams to deepen or broaden areas of particular intellectual interest.You will be encouraged to continue to expand your professional network both internal and external to Recursion.

#LI-CP1

At Recursion, we believe that every employee should be compensated fairly. Based on the skill and level of experience required for this role, the estimated current annual base range for this role is:

  • Developing:  TBD
  • Skilled: TBD
  • Expert: TBD

To learn more about our level within levels, click here.

You will also be eligible for bonuses and equity compensation + our comprehensive benefits package for United States based candidates. The range displayed on each job posting reflects target ranges for US new hire salaries and is determined by job, level, and market factors.  

During the interview selection process, you will connect with a Talent Acquisition Partner who will be your advocate and ally to ensure you receive the appropriate compensation that meets your needs for your skills, experience, and relevant education/training, while also reviewing our very competitive total rewards package.

The Values That We Hope You Share:

  • We Care: We care about our drug candidates, our Recursionauts, their families, each other, our communities, the patients we aim to serve and their loved ones. We also care about our work.
  • We Learn: Learning from the diverse perspectives of our fellow Recursionauts, and from failure, is an essential part of how we make progress.
  • We Deliver: We are unapologetic that our expectations for delivery are extraordinarily high. There is urgency to our existence: we sprint at maximum engagement, making time and space to recover. 
  • Act Boldly with Integrity: No company changes the world or reinvents an industry without being bold. It must be balanced; not by timidity, but by doing the right thing even when no one is looking.
  • We are One Recursion: We operate with a 'company first, team second' mentality. Our success comes from working as one interdisciplinary team.

Recursion spends time and energy connecting every aspect of work to these values. They aren’t static, but regularly discussed and questioned because we make decisions rooted in those values in our day-to-day work. You can read more about our values and how we live them every day here.

More About Recursion 

Recursion is a clinical stage TechBio company leading the space by decoding biology to industrialize drug discovery. Enabling its mission is the Recursion OS, a platform built across diverse technologies that continuously expands one of the world’s largest proprietary biological and chemical datasets. Recursion leverages sophisticated machine-learning algorithms to distill from its dataset a collection of trillions of searchable relationships across biology and chemistry unconstrained by human bias. By commanding massive experimental scale — up to millions of wet lab experiments weekly — and massive computational scale — owning and operating one of the most powerful supercomputers in the world, Recursion is uniting technology, biology and chemistry to advance the future of medicine.

Recursion is headquartered in Salt Lake City, where it is a founding member of BioHive, the Utah life sciences industry collective. Recursion also has offices in London, Toronto, Montreal and the San Francisco Bay Area. Learn more at www.Recursion.com, or connect on X (formerly Twitter) and LinkedIn.

Recursion is an Equal Opportunity Employer that values diversity and inclusion.  All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, disability, veteran status, or any other characteristic protected under applicable federal, state, local, or provincial human rights legislation. 
Recursion welcomes and encourages applications from people with disabilities. Accommodations are available on request for candidates taking part in all aspects of the selection process.

Recruitment & Staffing Agencies: Recursion Pharmaceuticals and its affiliate companies do not accept resumes from any source other than candidates. The submission of resumes by recruitment or staffing agencies to Recursion or its employees is strictly prohibited unless contacted directly by Recursion’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of Recursion, and Recursion will not owe any referral or other fees. Our team will communicate directly with candidates who are not represented by an agent or intermediary unless otherwise agreed to prior to interviewing for the job.

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